BSC Classification

The Biopharmaceutics Classification System (BCS) for drugs, or the classification of Biosafety Cabinets (BSCs) used in laboratories.

ClassProtection TargetAirflow DesignApplicationsRemarks
Class I✅ Protect user
✅ Protect environment
❌ Do not protect product		Front air inlet → HEPA filter → air exhaustSuitable for low-risk pathogen handling and simple sample manipulation in microbial experiments involving non-volatile, toxic, or radioactive substancesSimple structure, similar to a Fume Hood
Class II A2✅ Protect user
✅ Protect product
✅ Protect environment		70% Re-circulated air (after filtered through HEPA)
30% air exhaust after filtered through HEPA		適用於第1~3類病原微生物
細胞培養、血液樣本、無菌藥物調製		Most common type, suitable for most medical/research labs
Class II B1✅ Protect user
✅ Protect product
✅ Protect environment		約 70% 外排（經 HEPA）
約 30% 循環		適用於第1~3類病原微生物
從事微量具揮發性、毒性物質或放射性物質之實驗		Has a larger air exhaust volume than A2 type. Need to connect with an external air duct
Class II B2✅ Protect user
✅ Protect product
✅ Protect environment		100% air exhaust (through HEPA filter)適用於第1~3類病原微生物
從事具揮發性、毒性物質或放射性物質之實驗		High cost, high energy consumption. Requires a dedicated air exhaust system
Class III✅✅ Highest Level: Protect user + product + environmentFully enclosed and operates with attached gloves
Double HEPA filtration or HEPA filter with exhaust air incineration		適用於第3~4類病原微生物
高風險病原（BSL-3/4）、危險病毒或細菌操作		又稱「Class III 全密閉式生物安全櫃」，最嚴格的生物安全設施
 2025-08-28